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Your Position: Start > Fc gamma RIIB/C / CD32b/c

Fc gamma RIIB/C / CD32b/c

Brief Information

Name:Low affinity immunoglobulin gamma Fc region receptor II-b
Target Synonym:IgG Fc Receptor II-C,Fc Fragment Of IgG, Low Affinity IIb, Receptor (CD32),Fc Gamma Receptor IIb,IgG Fc Receptor II-B,Fc-Gamma RII-B,FcRII-B,CDw32,FCG2,Low Affinity Immunoglobulin Gamma Fc Region Receptor II-B,Fc Fragment Of IgG, Low Affinity II, Receptor For (CD32),Fc Gamma RIIb,CD32 Antigen,CD32B,FCGR2,Fc-gamma-RIIb,FCGR2B,IGFR2,CD32,Fc Fragment Of IgG Receptor IIb,Fc-Gamma RII-C,Low Affinity Immunoglobulin Gamma Fc Region Receptor II-C,Fc Fragment Of IgG, Low Affinity IIb, Receptor For (CD32)
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:5
Lastest Research Phase:Phase 3 Clinical

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CDB-H5284 Human Human Fc gamma RIIB/C (CD32b/c) Protein, Strep Tag (MALS & SPR verified)
CDB-H5284-structure
CDB-H5284-sds
CDB-H5298 Human Human Fc gamma RIIB/C (CD32b/c) Protein, SUMO,His Tag (MALS & BLI verified)
CDB-H5298-structure
CDB-H5298-sds
CDB-H52S9 Human Human Fc gamma RIIB/C (CD32b/c) Protein, HSA,His Tag (MALS & BLI verified)
CDB-H52S9-structure
CDB-H52S9-sds
CDB-H82E0 Human Biotinylated Human Fc gamma RIIB/C (CD32b/c) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)
CDB-H82E0-structure
CDB-H82E0-sds
CDB-H5228 Human Human Fc gamma RIIB/C (CD32b/c) Protein, His Tag (SPR & BLI & MALS verified)
CDB-H5228-structure
CDB-H5228-sds
ACRO Quality

Part of Bioactivity data

CDB-H5284-SPR
Fc gamma RIIB/C / CD32b/c SPR

Human CD32b/c Protein, Strep Tag (Cat. No. CDB-H5284) immobilized on CM5 Chip can bind Rituximab with an affinity constant of 10.2 μM as determined in a SPR assay (Biacore 8K) (QC tested).

Protocol
CDB-H5284-SPR
Fc gamma RIIB/C / CD32b/c SPR

Rituximab immobilized on CM5 Chip can bind Human CD32b/c Protein, Strep Tag (Cat. No. CDB-H5284) with an affinity constant of 5.18 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Obexelimab XmAb-5871; AMG-729 Phase 3 Clinical Xencor Inc Immunoglobulin G4-Related Disease; Lupus Erythematosus, Systemic Details
PRV-3279 HDM-3002; MGD-010; PRV-3279; CD32BxCD79B Phase 2 Clinical Macrogenics Inc Lupus Erythematosus, Systemic Details
BI-1206 6G-11; BI-1206 Phase 2 Clinical Bioinvent International Ab Lymphoma, B-Cell; Solid tumours; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia; Leukemia, Lymphocytic, Chronic, B-Cell Details
BI-1607 BI-1607 Phase 2 Clinical Bioinvent International Ab Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Metastatic breast cancer; Adenocarcinoma Details
NVG-2089 NVG-2089 Phase 1 Clinical Nuvig Therapeutics Inc Details
Obexelimab XmAb-5871; AMG-729 Phase 3 Clinical Xencor Inc Immunoglobulin G4-Related Disease; Lupus Erythematosus, Systemic Details
PRV-3279 HDM-3002; MGD-010; PRV-3279; CD32BxCD79B Phase 2 Clinical Macrogenics Inc Lupus Erythematosus, Systemic Details
BI-1206 6G-11; BI-1206 Phase 2 Clinical Bioinvent International Ab Lymphoma, B-Cell; Solid tumours; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia; Leukemia, Lymphocytic, Chronic, B-Cell Details
BI-1607 BI-1607 Phase 2 Clinical Bioinvent International Ab Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Metastatic breast cancer; Adenocarcinoma Details
NVG-2089 NVG-2089 Phase 1 Clinical Nuvig Therapeutics Inc Details

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